Derek Thompson (Dwayne "The Rock" Johnson) is "The Tooth Fairy", a hard-charging minor league hockey player whose nickname comes from his habit of separating opposing players from their bicuspids. When Derek discourages a youngster's hopes, he's sentenced to one week's hard labor as a real tooth fairy, complete with the requisite tutu, wings, and magic wand. At first, Derek "can't handle the tooth" - bumbling and stumbling as he tries to furtively wing his way through strangers' homes - doing what tooth fairies do. But as Derek slowly adapts to his new position, he begins to rediscover his own forgotten dreams.
